梁雪芳
个人简历
姓名：梁雪芳
职称：副教授/硕士生导师
所在单位：77779193永利
Tel：0471-4991679
Email:liangxf@imu.edu.cn
通讯地址：内蒙古呼和浩特市赛罕区大学西路235号
研究方向：
● 水生态毒理学
● 化学品毒性效应评价
● 新兴污染物的分子毒理与损伤
学习/工作经历：
● 2005.9~2009.7，吉林大学环境与资源学院，环境科学专业，本科；
● 2009.9~2014.7，中国科学院生态环境研究中心，环境科学专业，硕博连读；
● 2014.8~2017.11，77779193永利（原环境与资源学院），讲师
● 2017.12至今，77779193永利，副教授
● 2016.12- 2017.12，美国佛罗里达大学，环境与人类毒理学中心，访问学者
● 2019.7.14~7.28，中澳青年科学家交流计划项目，访问纽卡斯尔大学和昆士兰大学。
学术任职：
2018~ Comparative Biochemistry and Physiology杂志编委
2018~ Frontiers in Genetics杂志编委(Review Editor in Toxicogenomics)
科研项目（主持）：
1. 国家自然科学基金地区基金项目(21866024)：苯并三唑紫外稳定剂对鱼类的神经免疫毒性效应及其作用机制研究，2019.01-2022.12
2. 国家自然科学基金青年基金项目(21507064)：苯并三氮唑及其衍生物的分子作用位点甄选和作用机制研究，2016.01-2018.12
3. 内蒙古自治区高校青年科技英才计划项目(NJYT-20-B01)，2020.01-2021.12
4. 内蒙古自治区自然科学基金面上项目(2015MS0202)：苯并三氮唑及其衍生物对鱼类的分子靶和作用机制研究，2015.01-2017.12
5. 中国科学院饮用水科学与技术重点实验室开放基金课题（18K03KLDWST）：基于AOP分析苯并三唑类紫外吸收剂复合污染对鱼类的生殖毒性，2018.01-2019.12
6. 2014年引进博士科研启动项目（21800-5145146）
发表论文：
2019年：
1. Liang X, AdamovskyO, Souders II CL, Martyniuk CJ. Biological effects of the benzotriazole ultraviolet stabilizers UV-234 and UV-320 in early-staged zebrafish (Danio rerio). Environmental Pollution.2019, 245: 272-281.
2. Li Z, Li W, Zha J, Chen H, Martyniuk CJ, Liang X*. Transcriptome analysis reveals benzotriazole ultraviolet stabilizers regulate networks related to inflammation in juvenile zebrafish (Danio rerio) brain. Environmental Toxicology. 2019, 34(2):112-122.
3. Souders II CL, Davis RH, Qing H, Liang X, Febo M, Martyniuk CJ. The psychoactive cathinone derivative pyrovalerone alters locomotor activity and decreases dopamine receptor expression in zebrafish (Danio rerio). Brain and Behavior 2019, 9: e01420.
4. Chen H, Gu X, Zhang Q, Mao Z, Liang X, Martyniuk CJ. Carbamazepine disrupts molting hormone signaling and inhibits molting and growth of Eriocheir sinensis at environmentally relevant concentrations. Aquatic Toxicology 2019, 208: 138-145.
5. Cao F, Souders II, CL, Li P, Pang S, Liang X, Qiu L, Martyniuk CJ. Developmental neurotoxicity of maneb: notochord defects, mitochondrial dysfunction and hypoactivity in zebrafish (Danio rerio) embryos and larvae. Ecotoxicol Environ Saf 2019, 170: 227-237.
6. 仝天衡，杨慧婷，陈辉辉，梁雪芳*，谷孝鸿. 紫外吸收剂在湖泊中的分布及其对底栖动物的毒性效应[J]. 生态毒理学报, 2019, 14(3): 1-17
2018年：
7. Souders II CL, Liang X#, Wang X, Ector N, Zhao YH, Martyniuk CJ. High-throughput assessment of oxidative respiration in fish embryos: advancing adverse outcome pathways for mitochondrial dysfunction. Aquatic Toxicology (IF2017=3.884) 2018, 199: 162-173
8. Liang X, Feswick A, Simmons D, Martyniuk CJ. Environmental toxicology and omics: a question of sex. Journal of Proteomics (IF2017=3.722) 2018, 172: 152-164. (10 February 2018) doi: 10.1016/j.jprot.2017.09.010
9. Yan S, Wang M, Liang X, Martyniuk CJ, Zha J, Wang Z. Environmentally relevant concentrations of carbamazepine induce liver histopathological changes and a gender-specific response in hepatic proteome of Chinese rare minnows (Gobiocypris rarus). Environmental Pollution 2018, 243: 480-491.
10. 李雯镜, 李志彤, 梁雪芳*. 苯并三唑类紫外稳定剂在环境中的检测、分布及其毒性效应[J]. 生态毒理学报, 2018, 13(1): 900-905
2017年：
11. Liang X, Souders II CL, Zhang J, Martyniuk CJ. Tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio) embryos/larvae at environmentally relevant levels. Chemosphere (IF2016=4.208) 2017, 189, 498-506.
12. Liang X*, Zha J, Martyniuk CJ, Wang Z, Zhao J. Histopathological and proteomic responses in male Chinese rare minnow (Gobiocypris rarus) indicate hepatotoxicity following benzotriazole exposure. Environmental Pollution (IF2016=5.099) 2017, 229: 456-469.
13. Liang X*, Li J, Martyniuk CJ, Wang J, Mao Y, Lu H, Zha J. Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere (IF2016=4.208) 2017, 182: 22-30.
2016年以前：
14. Liang X, Martyniuk CJ, Zha J, Wang Z. Brain quantitative proteomic responses reveal new insight of benzotriazole neurotoxicity in female Chinese rare minnow (Gobiocypris rarus). Aquatic Toxicology (IF2016=4.129)2016, 181: 67-75
15. Liang X, Zha J. Toxicogenomic applications of Chinese rare minnow (Gobiocypris rarus) in aquatic toxicology. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics (IF2016=2.857) 2016, 19: 174-180.
16. 梁雪芳，赵吉，查金苗，王子健. 磷酸化蛋白质组学技术的发展及其在环境毒理研究中的应用．环境科学学报, 2016, 36(2): 398-412.
17. Liang X, Li W, Martyniuk CJ, Zha J, Wang Z, Cheng G, Geisy JP. Effects of dechlorane plus on the hepatic proteome of juvenile Chinese sturgeon (Acipenser sinensis). Aquatic Toxicology (IF2014=3.451) 2014, 148:83-91.
18. Liang X, Martyniuk CJ, Cheng G, Zha J, Wang Z. Pyruvate carboxylase as a sensitive protein biomarker for exogenous steroid chemicals. Environmental Pollution (IF2014=4.143)2014, 189:184-193.
19. Liang X, Wang M, Chen X, Zha J, Chen H, Zhu L, Wang Z. Endocrine disruption effects of benzotriazole on rare minnow (Gobiocypris rarus) in a sex-dependent manner. Chemosphere (IF2014=3.34) 2014, 112:154-162.
20. Chen H, Zha J, Liang X, Li J, Wang Z. Effects of the human antiepileptic drug carbamazepine on the behavior, biomarkers, and heat shock proteins in the Asian clam Corbicula fluminea. Aquatic Toxicology 2014, 155: 1-8.
21. Chen H, Zha J, Liang X, Wang M, Bu J, Wang Z. Sequencing and de novo assembly of the Asian clam (Corbicula fluminea) transcriptome using the Illumina GAIIx method. PloS ONE
22. 梁雪芳，查金苗，程钢，王子健. 蛋白质组学技术发展及在水生态毒理学中的应用. 生态毒理学报, 2012,7(1): 10-24.2013, 8(11): e79516.
会议报告
1. 典型BUVSs对鱼类的毒性效应研究进展, 第十届全国环境化学大会，2019.08，天津（口头报告）
2. 环境中典型塑料添加剂对鱼类的毒性和毒理, 第一届内蒙古大学生物学一流学科建设交叉学科讨论会, 2019.10, 呼和浩特 (分会邀请报告)
3. Liang X, Martyniuk C J, Cheng G, Zha J, Wang Z. Toxicology pathways of dechlorane plus based on hepatic proteome profile of juvenile Chinese sturgeon (Acipenser Sinensis). SETAC North America 34th Annual Meeting. (Poster)
4. Liang X, Souders II, C.L., Zhang, J., Martyniuk, C.J. Environmentally-relevant exposure to tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio). SETAC North America 38th Annual Meeting. (Poster)
荣誉和奖励
内蒙古大学2016年度校级大学生创新创业训练计划优秀项目（三等奖）、优秀指导教师
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